Bevacizumab

Pronounced

"bev-ah-CIZ-oo-mab"

Common brand names:

Avastin

Uses

This medication is a man-made antibody (IgG1) used to treat various types of cancer. This drug works by blocking a certain protein (vascular endothelial growth factor-VEGF) thereby decreasing the blood supply to the tumor and slowing tumor growth.

This monograph is about the following bevacizumab products: bevacizumab, bevacizumab-adcd, bevacizumab-awwb, bevacizumab-bvzr, and bevacizumab-maly.

Other Uses

This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used for certain serious eye conditions (such as age-related macular degeneration, macular edema).

How to Use This Medication

This medication is given by infusion into a vein by a health care professional. The first dose is usually given over 90 minutes. If you tolerate the first dose well, then later infusions may be given over a shorter time (60 or 30 minutes).

Infusion reactions may happen while you are receiving this medication. Tell your health care professional right away if you have symptoms such as difficulty breathing, flushing, severe dizziness, nausea/vomiting, shaking, or chest pain. Your health care professional will monitor you closely during your infusion. Your infusion may be slowed down or stopped depending on your symptoms.

The dosage is based on your medical condition, weight, and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, mark the days on the calendar when you need to receive the medication.

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