Vancomycin-Water Inject (Peg)

Warning

Vancomycin injection solution with PEG-400 and NADA is not recommended for use during the first or second trimester of pregnancy. PEG-400 and NADA may harm an unborn baby. Tell your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. Your doctor can prescribe another vancomycin product that can be used during pregnancy.

Precautions

Before using vancomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, hearing problems, stomach/intestinal problems (such as colitis).

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Vancomycin may cause live bacterial vaccines (such as typhoid vaccine) to not work well. Tell your health care professional that you are using vancomycin before having any immunizations/vaccinations.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Children may be at greater risk for severe infusion reactions when this medication is injected too fast. See also Side Effects section for details.

Older adults may be at greater risk for kidney and hearing problems while using this drug.

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using this product. Vancomycin solution with PEG-400 and NADA may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. See also Warning section.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Side Effects

Pain, redness, and tenderness at the injection site may occur. If this medication is injected too fast, an infusion reaction may occur. Tell your doctor promptly if you have symptoms such as flushing of the upper body, dizziness, or muscle pain/spasms of the chest and back. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: hearing problems (such as ringing in the ears, hearing loss), signs of kidney problems (such as change in the amount of urine), easy bleeding/bruising, vision changes (such as blurred vision, decreased vision).

This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool.

If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever that doesn't go away, new or worsening lymph node swelling, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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