Afamitresgene Autoleucel

Uses

Afamitresgene autoleucel is used to treat a certain type of cancer (synovial sarcoma) that has not gotten better or that has come back after other kinds of treatment. This type of treatment is known as gene therapy. Afamitresgene autoleucel is made from your own white blood cells and is given only to you. The white blood cells have been changed to have a specific protein that helps your body slow or stop the growth of certain cancer cells.

How to Use This Medication

Read the Medication Guide provided by your healthcare professional before you start using this product. If you have any questions, ask your healthcare professionals.

Your doctor may give you 4 days of chemotherapy before treatment with this product to prepare your body.

This product is given by slow injection into a vein as directed by your doctor, usually over less than 60 minutes. To decrease the risk of side effects, your doctor may also give you other medications (such as acetaminophen, diphenhydramine) before injecting afamitresgene autoleucel.

Your doctor will check you daily for at least 7 days after your treatment to see how well it works and help you manage any side effects. You should plan to stay for at least 4 weeks near the place of your treatment (for example, within 2 hours' drive).

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Information expires December 2025.

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