Norelgestrom-Ethinyl Estradiol

Pronounced

"ETH-in-il ess-tra-DYE-ole/nor-el-JESS-troh-min"

Common brand names:

Evra

Uses

This patch contains combination hormone medication and is used to prevent pregnancy. It contains 2 hormones: a progestin (norelgestromin) and an estrogen (ethinyl estradiol).

This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.

How to Use This Medication

Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. The leaflet contains very important information on how to properly use and dispose of the patch. If you have any questions, ask your doctor or pharmacist.

Do not cut or damage the patch. Remove the patch from the foil pouch and apply as directed by the manufacturer to clean, dry skin on the upper outer arm, abdomen, buttock, or upper body where it will not be rubbed by tight clothing. Do not apply the patch to your breasts or on red/cut/irritated skin. Do not use lotions, creams, oils, powders, or make-up at the patch site, since it may not stick properly or may fall off.

If this is your first time using this medication, apply the patch on the first Sunday following the beginning of your menstrual period or on the first day of your period. If your period begins on a Sunday, begin on that day. For the first cycle of use only, use a backup form of non-hormonal birth control (such as condoms, spermicide) for the first 7 days to prevent pregnancy until the medication has enough time to work. If you start using the patch on the first day of your period, you do not need to use backup birth control the first week.

Change the patch once a week on the same day. Remove the used patch before placing a new one. Apply the patch to a different area with each change to avoid skin irritation. After wearing patches for 3 weeks in a row, do not wear a patch during week 4. You should have your period during this time. After not wearing a patch for a week, apply a new patch whether or not you have your period. If you do not get your period, consult your doctor. Do not go longer than 7 days without a patch, since this will increase your chance of pregnancy. To help you remember, mark your calendar to remind yourself when to change or leave off patches.

If the patch falls off, re-apply it or apply a new patch within 24 hours. If the patch is not replaced within 24 hours, or if you are not sure how long it has been off, start a new cycle by applying a new patch and use a backup form of non-hormonal birth control (such as condoms, spermicide) for the next 7 days to prevent pregnancy.

After removing each patch, fold it in half so it sticks to itself, and discard in the trash away from children and pets. Do not flush the patch down the toilet.

Ask your doctor or pharmacist about how to switch from other forms of hormonal birth control (such as birth control pills) to this product. If any information is unclear, consult the Patient Information Leaflet or your doctor or pharmacist.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.