Omadacycline

This form:

Pronounced

"oh-MAD-a-SYE-kleen"

Uses

Omadacycline is used to treat a wide variety of bacterial infections. This medication belongs to a class of drugs known as tetracycline antibiotics. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

How to Use This Medication

Take this medication by mouth on an empty stomach as directed by your doctor, usually once daily. Fast for at least 4 hours before your dose, then take your dose with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. After taking this medication, you may drink water, but do not eat food or drink other liquids for 2 hours after taking this medication. Also, do not lie down for at least 10 minutes after taking your dose.

Take this medication at least 4 hours before or after taking any products containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate. Some examples include antacids, quinapril, sucralfate, vitamins/minerals, dairy products (such as milk, yogurt), and calcium-enriched juice. These products bind with omadacycline, preventing your body from fully absorbing the drug.

The dosage and length of treatment are based on your medical condition and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition does not get better or if it gets worse.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.