Taken as recommended, goldenseal is generally safe. However, as with all alkaloid-containing plants, high amounts (several times higher than the recommended amounts) may lead to gastrointestinal distress and possible nervous system effects.7 Goldenseal is not recommended for pregnant or breast-feeding women. Also, despite some traditional reports, goldenseal is not a substitute for antibiotics.
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.