"val-PRO-ate SO-dee-um"
Depakene
This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking valproate sodium and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor. You may take it with food if stomach upset occurs.
Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Valproate sodium syrup should not be mixed with carbonated drinks because it may irritate the mouth and throat.
The dosage is based on your age, weight, medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
This medication does not relieve acute migraine headaches. Take other medications as directed by your doctor for acute attacks.
Tell your doctor if your condition does not get better or if it gets worse.
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Information expires December 2026.