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Low Back Pain
| Supplement | Amount | Why |
|---|---|---|
Chymotrypsin and Trypsin | 4 to 8 tablets a day of proteolytic enzymes containing trypsin and chymotrypsin, and/or bromelain |  [3 stars] Supplementing with a combination of the enzymes trypsin and chymotrypsin may improve low back pain. |
Phenylalanine | 1,500 to 2,500 mg per day of DL-Phenylalanine |  [2 stars] Several studies suggest that a synthetic version of phenylalanine called D-phenylalaline, may reduce pain by decreasing the enzyme that breaks down endorphins. |
Vitamin B1, Vitamin B6, and Vitamin B12 | Take under medical supervision: 50 to 100 mg each of vitamins B1 and B6, and 250 to 500 mcg of vitamin B12, all taken three times per day | [2 stars] A combination of vitamin B1, vitamin B6, and vitamin B12 may prevent a common type of back pain linked to vertebral syndromes and may reduce the need for anti-inflammatory medications. |
Vitamin D | Refer to label instructions | [2 stars] In people with muscle pain associated with vitamin D deficiency, supplementing with the vitamin may improve pain.
|
White Willow | Take an extract supplying 240 mg of salicin daily | [2 stars] Willow bark is traditionally used for pain and conditions of inflammation. According to one study, taking high amounts of willow bark extract may help people with low back pain. |
Bromelain | 4 to 8 tablets a day of proteolytic enzymes containing trypsin and chymotrypsin, and/or bromelain |  [1 star] Several trials have reported reduced pain and swelling, and/or faster healing in people with a variety of conditions who use bromelain. |
Chili Peppers | Refer to label instructions | [1 star] Topical cayenne pepper has been used for centuries to reduce pain and to diminish localized pain for a number of conditions. |
Devil’s Claw | Refer to label instructions | [1 star] One trial found that devil’s claw capsules were helpful in reducing acute low back pain in some people. |
Eucalyptus Topical | Refer to label instructions | [1 star] A combination of eucalyptus and peppermint oil applied directly to a painful area may help by decreasing pain and increasing blood flow to afflicted regions. |
Ginger | Refer to label instructions | [1 star] Herbalists often use ginger to decrease inflammation and the pain associated with it, including for those with low back pain. |
Papain | Refer to label instructions | [1 star] Several trials have reported reduced pain and swelling, and/or faster healing in people with a variety of conditions who use papain. |
Peppermint | Refer to label instructions | [1 star] A combination of eucalyptus and peppermint oil applied directly to a painful area may help by decreasing pain and increasing blood flow to afflicted regions. |
Turmeric (Curcumin) | Refer to label instructions | [1 star] Turmeric is an herb known traditionally for its anti-inflammatory effects, a possible advantage for people suffering from low back pain. |
Vitamin C | Refer to label instructions | [1 star] A preliminary report suggested that vitamin C helped many people avoid surgery for their disc-related low back pain. |
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
Copyright © 2025 TraceGains, Inc. All rights reserved.
Learn more about TraceGains, the company.
The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.
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