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Cenobamate

Pronounced

"SEN-oh-BAM-ate"

Common brand names:

Xcopri

Uses

This medication is used to treat a certain type of seizure disorder (partial onset). It is not known exactly how it works, but it may affect the action of some nerves that cause seizures.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start taking cenobamate and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.

If needed, you may also crush the tablet(s). Mix the crushed tablet(s) with water (1 ounce or 25 milliliters) in a cup. Swirl to mix and drink the suspension right away. Refill the cup with more water (1 ounce or 25 milliliters) and drink the mixture to make sure you are getting the whole dose. Repeat until there are no more tablet pieces left in the cup. Do not save the mixture for future use.

If you are giving this medication through a feeding tube, ask your health care professional for detailed instructions on how to properly mix and give it.

To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not stop taking this medication without consulting your doctor. Some conditions (such as seizure) may become worse when this drug is suddenly stopped. Also, suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly over at least 2 weeks. Tell your doctor or pharmacist right away if you have any withdrawal symptoms such as decreased appetite or mental/mood changes such as depression, loss of memory, trouble sleeping.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Keep this medicine in a safe place to prevent theft, misuse, or abuse.

Tell your doctor if your condition does not get better or if it gets worse.

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RxAnswers™ is a copyrighted combined product from TraceGains and First DataBank, Inc.

Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.