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Ecallantide

Pronounced

"e-KAL-lan-tide"

Uses

This medication is used to treat an acute attack of a certain immune disease passed down through families (hereditary angioedema-HAE). Ecallantide blocks a natural substance produced by the body (kallikrein) which acts to increase amounts of another natural substance (bradykinin) thought to cause the symptoms seen during an acute attack of HAE. This medication does not cure HAE. Ecallantide may lessen the symptoms during an acute attack of HAE such as rapid swelling and pain of the hands, feet, limbs, face, tongue, or throat. When attacks involve the intestines, symptoms may include abdominal pain/cramps, diarrhea or vomiting. Attacks of swelling may occur without reason. However, anxiety, stress, sickness, and surgery may trigger attacks in some people.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start using ecallantide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection under the skin by a healthcare professional. It is given as directed by your doctor, usually as three separate shots which are spaced by at least 2 inches (5 centimeters) apart. An additional three shots may be given in a 24-hour period if the HAE attack continues. The injection is given in the abdomen, thigh, or upper arms. The medication should not be injected into skin that is tender, red, or hard.

Tell your doctor if your condition does not improve or if it worsens.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.