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Edoxaban

Pronounced

"e-DOX-a-ban"

Common brand names:

Lixiana

Uses

Edoxaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation). It is also used to treat certain blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE).

Edoxaban is an anticoagulant that works by blocking certain clotting proteins in your blood.

How to Use This Medication

See also Warning section.

Read the Medication Guide provided by your pharmacist before you start taking edoxaban and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you have trouble swallowing the tablet whole, you may crush the tablet and mix it with 2 to 3 ounces (60 to 90 milliliters) of water or applesauce. Drink or eat the entire mixture right away. Do not prepare a supply for future use.

If you are giving this medication through a tube into the stomach (gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.