Read the Medication Guide provided by your pharmacist before you start taking lemborexant and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take lemborexant by mouth as directed by your doctor, usually right before you get into bed. This medication can be taken with or without food, but it may take longer to work if you take it with or right after a meal. Do not take this medication with alcohol or with other drugs that help you sleep.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Do not take a dose of this drug unless you have time for a full night's sleep of at least 7 hours. If you have to wake up before that, you may have trouble safely doing anything that needs alertness, such as driving or operating machinery. (See also Precautions section.)

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Do not increase your dose, take it more often, or use it for longer than prescribed. Your condition will not improve any faster and your risk of side effects will increase.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your condition lasts after 7 to 10 days, or if it gets worse.