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Polyethylene Glycol 3350

Pronounced

"paw-lee-ETH-ih-leen GLY-coll"

Common brand names:

Pegalax

Uses

This medication is used to treat occasional constipation. It works by holding water in the stool to soften the stool and increases the number of bowel movements. It is known as an osmotic-type laxative.

This medication is also available without a prescription. If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist. (See also Precautions.)

How to Use This Medication

Take this medication by mouth usually once daily, or as directed by your doctor or the directions on the product package.

If you are prescribed the individual packets, mix the powder as directed by your doctor or pharmacist. If you are using the bulk bottle, use the provided cap to measure the prescribed dose. Mix the powder with a glass (4-8 ounces/120-240 milliliters) of liquid such as water, juice, soda, coffee, or tea. Before drinking the solution, stir the powder well until it completely dissolves. If you have any questions, ask your pharmacist.

This medication may cause certain liquid thickeners (starch-based products) to not work well, which may increase the risk of choking. If you are using liquid thickeners with this medication, talk to your pharmacist to select a liquid thickener which will not interact with this medication.

It may take 2 to 4 days after you have started this medication to have a bowel movement. Do not increase your dose or take it more often than prescribed. Also, do not use this medication for more than 2 weeks unless directed by your doctor. Tell your doctor if your condition lasts or gets worse. Extended use or overuse may result in dependence on laxatives and chronic constipation. Overuse may cause diarrhea, dehydration, and mineral imbalance (such as low sodium).

If you are using nonprescription polyethylene glycol for self-treatment of occasional constipation and this treatment has not worked after 7 days, talk to your doctor for additional treatment advice.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

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Information expires December 2025.