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Trifarotene

Pronounced

"trye-FAR-oh-teen"

Common brand names:

Aklief

Uses

This medication is used to treat acne. It may decrease the number and severity of acne pimples and speed up healing of pimples that do develop. Trifarotene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

How to Use This Medication

Read the Patient Information Leaflet if available from your pharmacist before you start using trifarotene and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication as directed by your doctor, usually once daily in the evening. Before using, gently clean the affected skin with a mild or soapless cleanser and pat dry.

Wash your hands before and after applying this medication. Apply a small amount of medication in a thin layer on the affected area(s).

Use this medication on the skin only. Avoid getting this medication in your eyes or on your lips. Do not apply to the inner lip area or inside the nose/mouth. If this medication gets in your eyes, flush with large amounts of water. Call your doctor if eye irritation develops. Do not apply to cut, scraped, or sunburned areas, or to skin affected by eczema (a skin condition).

When you begin using this medication, you should also apply a moisturizer on your skin as often as needed to help lessen skin irritation (see also Side Effects section).

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not use a larger amount or use it more often than directed. Your skin will not improve any faster, and your risk of developing side effects (such as redness, peeling, or pain) will increase.

Tell your doctor if your condition does not get better or if it gets worse.

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Drug information is selected from data included with permission and copyrighted by First DataBank, Inc. This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional. Always seek the advice of your healthcare professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your healthcare professional. This information does not contain any assurances that this product is safe, effective or appropriate for you.

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Information expires December 2025.