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Conjugated Linoleic Acid

Also indexed as:CLA, Linoleic Acid (Conjugated), Tonalin
Conjugated Linoleic Acid: Main Image

Conjugated linoleic acid (CLA) is a slightly altered form of the essential fatty acid linoleic acid.

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Obesity
1.7–8 grams daily2 stars[2 stars]
Although the evidence is conflicting, the majority of the evidence shows CLA can help people lose body fat, and may promote a small amount of weight loss.
Athletic Performance
Refer to label instructions 1 star[1 star]
Conjugated linoleic acid may play a role in reducing body fat. Research has reported that CLA supplementation produces minor gains in muscle size and strength in weight-training men.
Breast Cancer
Refer to label instructions 1 star[1 star]
Preliminary research suggests that CLA might reduce breast cancer risk.
Colon Cancer
Refer to label instructions 1 star[1 star]
Preliminary and test tube studies indicate that CLA may reduce the risk of colon cancer.
Lung Cancer
Refer to label instructions 1 star[1 star]
Preliminary research suggests that CLA might reduce the risk of cancers at several sites, including breast, prostate, colorectal, lung, skin, and stomach.
Multiple Sclerosis
Refer to label instructions 1 star[1 star]
Omega-6 fatty acids found in sunflower seed oil (a source of linoleic acid) may be beneficial. Studies have reported that linoleic acid reduced relapse severity and length and decreased disability due to MS.
Prostate Cancer
Refer to label instructions 1 star[1 star]
Preliminary research suggests that CLA might reduce the risk of cancers at several sites, including breast, prostate, colorectal, lung, skin, and stomach.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.