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Taliglucerase Alfa

Pronounced

"TAL-i-GLOO-ser-ase AL-fa"

Common brand names:

Elelyso

Uses

Taliglucerase is used to treat a certain rare genetic problem (Gaucher disease). Taliglucerase replaces a certain natural substance (an enzyme called glucocerebrosidase) that is missing in people with Gaucher disease.

This medication improves blood, bone, liver, and spleen problems caused by Gaucher disease. Taliglucerase does not correct the genetic problem, and treatment must be continued for life.

How to Use This Medication

This medication is given slowly over 1 to 2 hours into a vein as directed by your doctor, usually every 2 weeks. The dosage is based on your weight, medical condition, and response to treatment.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Do not shake while mixing the solution. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Discard any unused prepared medication. Do not save for later use. Learn how to store and discard medical supplies safely.

Allergic reactions may happen during the infusion of this drug and for some time afterward. Your doctor may prescribe other medications before each treatment to help prevent these side effects. Tell your doctor right away if you have any symptoms of allergic reactions such as headache, nausea/vomiting, dizziness, increased blood pressure, weakness/tiredness, back/joint pain, flushing, coughing. Your doctor may give you other medications to help with these side effects or may slow down or stop your treatment for some time.

Tell your doctor if your condition lasts or gets worse. Blood, liver, and spleen problems usually improve in the first year of treatment. It may take 2 to 3 years of treatment to see the full benefit to your bones.

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Information expires December 2024.