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Tardive Dyskinesia

Involuntary muscle tics may be a consequence of long-term “antipsychotic” medication use. According to research or other evidence, the following self-care steps may be helpful.
SupplementAmountWhy
Vitamin E
1,600 IU daily3 stars[3 stars]
Vitamin E has been shown to reduce the severity of tardive dyskinesia.
Ginkgo
240 mg daily2 stars[2 stars]
Ginkgo biloba extract EGb 761 improved symptoms of tardive dyskinesia by about 30% in schizophrenic patients.
Lecithin (Phosphatidyl Choline)
25 grams lecithin twice a day, providing 35 grams of phosphatidyl choline per day2 stars[2 stars]
Lecithin and phosphatidyl choline may help improve symptoms.
Manganese
For prevention: 15 mg daily while taking anti-psychotic medication; treat under a doctor's supervision: 60 mg daily2 stars[2 stars]
Supplementing with manganese may prevent onset or help reverse the condition.
Melatonin
Take under medical supervision: 10 mg daily at bedtime2 stars[2 stars]
Taking melatonin may help reduce abnormal movements.
Branched-Chain Amino Acids
Refer to label instructions 1 star[1 star]
Supplementing with branched-chain amino acids may reduce excess phenylalanine in people with tardive dyskinesia.
DMAE
Refer to label instructions 1 star[1 star]
Taking dimethylaminoethanol may help reduce symptoms.
Evening Primrose Oil
Refer to label instructions 1 star[1 star]
Several people have experienced improvement while taking evening primrose oil.
L-Tryptophan
Refer to label instructions 1 star[1 star]
Animal research and preliminary human reports suggest that L-tryptophan may help  reduce the severity of symptoms.
Vitamin B3 (Niacin)
Refer to label instructions 1 star[1 star]
In some studies, taking vitamin B3 as niacin or niacinamide, along with other nutrients, appeared to prevent the development of tardive dyskinesia.
Vitamin B6
Refer to label instructions 1 star[1 star]
In some studies, taking vitamin B6 along with other nutrients appeared to prevent the development of tardive dyskinesia.
Vitamin B-Complex
Refer to label instructions 1 star[1 star]
In some studies, taking vitamin B-complex along with other nutrients appeared to prevent the development of tardive dyskinesia.
Vitamin C
Refer to label instructions 1 star[1 star]
In some studies, taking vitamin C along with other nutrients appeared to prevent the development of tardive dyskinesia
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.