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L-Tryptophan

Also indexed as:Tryptophan
L-Tryptophan: Main Image

Interactions with Supplements, Foods, & Other Compounds

“Serotonin syndrome,” a serious but uncommon condition caused by excessive amounts of serotonin, has not been reported to result from supplementation with L-tryptophan, but it can be triggered by combining L-tryptophan with drugs that increase serotonin activity (such as certain antidepressants and certain drugs used to treat migraines).10, 11 Also, it is conceivable that L-tryptophan would increase the toxicity of St. John's wort.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.