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Oregon Grape

Also indexed as:Berberis aquifolium
Oregon Grape: Main Image© Steven Foster
Botanical names:
Berberis aquifolium

Parts Used & Where Grown

Oregon grape is an evergreen shrub which grows throughout the American northwest. It is somewhat misnamed, as the fruit are not actually grapes. It is, however, grown in Oregon (it is the official state flower). Oregon grape is a close relative of barberry (Berberis vulgaris), and shares many common uses and constituents. The root is used medicinally.

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Chronic Candidiasis
Refer to label instructions 1 star[1 star]
Oregon grape contains berberine, an alkaloid with antibiotic and antifungal activity that also been shown to help relieve the diarrhea seen in some people with chronic candidiasis.
Conjunctivitis and Blepharitis
Refer to label instructions 1 star[1 star]
Oregon grape contains berberine, an antibacterial constituent that has been clinically studied for eye infections.
Diarrhea
Refer to label instructions 1 star[1 star]
Berberine, a constituent of Oregon grape, has been shown to improve infectious diarrhea in some trials.
Indigestion, Heartburn, and Low Stomach Acidity
Refer to label instructions 1 star[1 star]
Oregon grape may stimulate digestion and relieve spasms in the intestinal tract.
Infection
Refer to label instructions 1 star[1 star]
Oregon grape is both immune supportive and antimicrobial.
Parasites
Refer to label instructions 1 star[1 star]
Berberine is derived from several plants, including Oregon grape. Studies have shown that berberine kills amoebae and can be used successfully to treat giardia infections.
Psoriasis
Refer to label instructions 1 star[1 star]
Oregon grape has been shown to be effective against moderate psoriasis and to reduce inflammation.
Urinary Tract Infection
Refer to label instructions 1 star[1 star]
Oregon grape contains berberine, an alkaloid that may prevent UTIs by inhibiting bacteria from adhering to the wall of the urinary bladder.

Traditional Use (May Not Be Supported by Scientific Studies)

Before European colonists arrived, the indigenous peoples of North America treated all manner of complaints with Oregon grape.1 The berries were used for poor appetite. A tea made from the root was used to treat jaundice, arthritis, diarrhea, fever, and many other health problems.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.